IgG Biosynthesis: No “Immunoregulatory Feedback”

IgG biosynthesis: no "immunoregulatory feedback".

Feedback regulation of iron-sulfur cluster biosynthesis.

I clusters ([Fe-S] clusters) represent one of nature’s simplest, functionally versatile, and perhaps most ancient prosthetic groups (1). Among the familiar types of [Fe-S] clusters are [2Fe2S] and [4Fe-4S] clusters, which usually are attached to their protein partners by four cysteine thiol ligands (Fig. 1). Proteins that contain one or more [Fe-S] clusters are commonly called [Fe-S] proteins, ...

IgG in Silkworm, and No Alterations in their N-Linked

Human 29IJ6 IgG was expressed in silkworm using a Bombyx mori 25 nucleopolyhedrovirus (BmNPV) bacmid system. The mean amounts of 296IJ6 IgG 26 produced in larval hemolymph and whole pupae were 30.1 μg/larva and 78.0 μg/pupa,

No-feedback Card Guessing for Dovetail Shuffles

We consider the following problem. A deck of 2n cards labeled consecutively from 1 on top to 2n on bottom is face down on the table. The deck is given k dovetail shuues and placed back on the table, face down. A guesser tries to guess at the cards one at a time, starting from top. The identity of the card guessed at is not revealed, nor is the guesser told whether a particular guess was correct...

Negative feedback in NO/cGMP signalling.

Most of the effects of the signalling molecule nitric oxide (NO) are mediated by the stimulation of the NO-sensitive GC (guanylate cyclase) and the subsequent increase in cGMP formation. The enzyme contains a prosthetic haem group, which mediates NO stimulation. In addition to the physiological activator NO, NO-sensitizers like the substance YC-1 sensitize the enzyme towards NO and may therefor...